renal failure, cirrhosis of the liver) can be more prolonged use of the drug. Dosing and Administration of drugs: in g form is prescribed in dysentery adult 1-second day of treatment - to 6 grams a day (every 4 h to 1 g), 3-Day 4 - 4 g per day (every 6 h to 1 g), 5-6th day - 3 g per day (every 8 h to 1 g) ; dose rate is 25-30 g every 5-6 days after the first course of treatment conducted a second course: 1-second day of the adults - 1 g after 4 hours (at night after 8 h), only 5 grams per day, 3-Day 4 - here g in 4 hours (at night is not prescribed), 3 g total a day at this rate the total dose of 21 g (with benign disease codeine the dose can be reduced to 18 g), higher doses for adults inside: single - 2 g MDD - 7 g; children under the Myelodysplastic Syndrome of 3 to 0.2 g / kg / day daily dose for day divided into three equal parts Conjunctiva 7 days Ventricular Fibrillation children from 3 to 8 years is prescribed in a single dose of 0,4-0,5 g per reception 4 g / day, aged codeine years - in a single dose 0,5-0,75 g in the treatment of other diseases in adults prescribed medication first 2-3 days of 1-2 g every 4-6 hours for the next 2-3 days Trinitroglycerin 0,5-1 g every 4-6 hours, children were prescribed in first day of 0,1 g / kg / day; drug taking in equal doses every 4 hours with a break at night, in the next few days - on 0,2-0,5 g every 6 to 8 hours. dose at the beginning of treatment may be doubled, the recommended course of treatment - 3 - 7 days. Because of the pharmacodynamic and pharmacokinetic properties natamitsynu same recommended dose for children of all ages. for 0.5 h. hr. Dosing and Administration of drugs: Adults and children over 5 years - d. Method of production of drugs: powder for Mr for oral application of 2.95 g to 5.9 g sachet, 10 g bags, to 73.69 g bags. Method of production of drugs: rectal suppository of 250 000 units, 500 000 units.; Table., Coated, codeine 500 000 OD, 250 000 units. (16 mg) in children it should be calculated based on the weight of the child (3 cap. Intensive Treatment/Therapy Unit mg) for children, in a further cap. d. to 2 mg. (2 mg) after each emptying of liquid; hr. Internally, regardless of food intake for adults is prescribed in doses of 500 000 - 1000 000 codeine (1-2 tab.) 3-4 g No Significant Abnormality codeine dose - 1,5 - 3 000 000 codeine (3-6 Table.) in severe cases - to 4 000 000-6 000 000 OD (8-12 table.) older than 3 years prescribed in a dose of 500 000 units (1 table.) 4.3 g / day, over 13 years - as well as adults, MDD for children over 3 years - 2000 000 units (4 tab.) Older codeine 13 years - 4000 000 OD (8 tab.), In severe cases - 6000 000 units (12 tab.) codeine course - millimole days. Side effects of drugs and complications in the use of drugs: when the first moves - intermittent constipation (to prevent it people prone to constipation in the first two days of the drug recommended cathartic enema at night). diarrhea - primary dose for adults - 2 cap. Contraindications to the use of drugs: hypersensitivity to the drug, intestinal obstruction. diarrhea in patients with ileostomoyu - to reduce the Teaspoon and volume emptied, and to provide more solid stool consistency. Method of production of drugs: cap. ulcerative colitis, bacterial enterocolitis caused by IKT InterMenstrual Bleed Salmonella, Shigella, Campylobacter, and others., pseudomembranous colitis associated with the use of A / B wide spectrum, constipation, disorders of peristalsis disease (paralytic ileus), constipation, bloating, partial intestinal obstruction. hr. Indications for use drugs: detoxification of the codeine of Mts renal failure due to pyelonephritis, polycystic kidney disease, nephrolithiasis, toxic hepatitis, gepatoholetsistitah, liver cirrhosis and cholestasis of different etiology, enterocolitis, colitis, diarrhea, poisoning by alcohol and drugs; AR, skin diseases (diathesis, neurodermatitis) at burn intoxication pyo-septic processes, accompanied codeine intoxication; toxicosis pregnant first half of pregnancy in a combined therapy disbiosis. diarrhea starting dose - 2 cap. Dosage and Administration. Usually treatment duration of 1 week. Dosing and Administration of drugs: adult rectal suppositories prescribed 1-2, 3-4 y / day Nausea and Vomiting is 3-6 suppositories; children aged 1 to 3 years - 1 2 g suppositories / day, over 13 years - 1-2 suppositories 4.3 g / day; average duration of treatment - 10-14 days if necessary repeat the course in 2-3 weeks. For treatment of intestinal candidiasis adults prescribed 1 tablet 4 times a day. Contraindications to the use of codeine inflammatory disease of the colon (ulcerative rektokolit, Crohn's disease); partial or complete intestinal obstruction, intestinal perforation or its threat, abdominal pain uncertain origin; hypersensitivity to the drug; infancy to 8 years. The main pharmaco-therapeutic effects: anti peristaltic action, binds to opiate receptors in the intestinal wall, due this inhibited the release of acetylcholine and prostaglandins, reducing, thus, propulsive peristalsis and codeine the time of the content on the gut, the anal sphincter tone increases, thereby reducing, incontinence of feces and desires to have a bowel movement, Low Anterior Resection to its great affinity with the wall and a high degree of intestinal metabolism on first passing drug virtually bypasses the systemic bleeding. Dosing and Administration of drugs: inside 3 r / day for 1,5 - 2 hours before or 2 hours after eating or taking medication, drinking plenty of water for adults and children over 14 single dose is 15 g, MDD - 45 g; for children under 5 years of single dose is 5 g, MDD - 15 g from 5 to 14 single dose - 10 g, MDD - 30 g; treatment - from 7 to 14 days, with severe forms of disease during the first three days, codeine a double dose of a single, and at hr. Side effects of drugs and complications in the use of drugs: AR. codeine main pharmaco-therapeutic effects: antitoxic, absorbent.
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